Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30159837 | 0.81 | PCSK9 (0.57) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL26104217 | 0.81 | PCSK9 (0.57) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL17297375 | 0.80 | HTR6 (0.67) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL29357508 | 0.80 | HTR6 (0.67) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL19876630 | 0.80 | PCSK9 (0.56) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL2019307 | 0.78 | AGTR1 (0.62) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL13276086 | 0.77 | KDM4E (0.58) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL22638213 | 0.77 | AGTR1 (0.62) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| SCHEMBL2023125 | 0.75 | HTR6 (0.53) | AGTR1HTR6KDM4EUBE2NALDH1A1 | |
| Formamide SCHEMBL28614180 | 0.75 | KDM4E (0.52) | AGTR1HTR6KDM4EUBE2NALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |