Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332462 | 0.96 | TSHR (0.43) | TSHRMETAP2NAAARAD52EPHX1 | |
| SCHEMBL2559507 | 0.92 | SIGMAR1 (0.40) | RENBCHESIGMAR1TSHRMETAP2 | |
| SCHEMBL29955496 | 0.86 | SIGMAR1 (0.36) | GAASIGMAR1RAD52EPHX1 | |
| SCHEMBL2561078 | 0.86 | EPHX2 (0.44) | GAASIGMAR1TSHRRAD52USP2 | |
| SCHEMBL15332980 | 0.83 | ALDH1A1 (0.41) | GAASIGMAR1TSHRNPSR1 | |
| SCHEMBL2557932 | 0.82 | EPHX1 (0.41) | SIGMAR1EPHX1 | |
| SCHEMBL2555121 | 0.82 | HPGD (0.33) | GAASIGMAR1EPHX1 | |
| SCHEMBL15329588 | 0.80 | XIAP (0.33) | SIGMAR1 | |
| SCHEMBL15330465 | 0.80 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL15329739 | 0.80 | ALDH1A1 (0.43) | SIGMAR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |