Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562163 | 0.88 | KDM4E (0.55) | POLBALDH1A1NPC1LMNAMAPT | |
| SCHEMBL15329632 | 0.84 | ALDH1A1 (0.58) | ALDH1A1NPC1MAOAMAOBRAB9A | |
| SCHEMBL29954389 | 0.82 | MAPT (0.64) | POLBALDH1A1NPC1LMNAMAPT | |
| SCHEMBL29952545 | 0.82 | ALDH1A1 (0.60) | ALDH1A1NPC1MAOAMAOBRAB9A | |
| SCHEMBL2654762 | 0.81 | MAOA (0.43) | POLBALDH1A1NPC1MAPTMAOA | |
| SCHEMBL31074700 | 0.81 | HSD17B10 (0.52) | POLBALDH1A1NPC1LMNAMAPT | |
| SCHEMBL2556295 | 0.81 | HSD17B10 (0.52) | POLBALDH1A1NPC1LMNAMAPT | |
| SCHEMBL18343117 | 0.80 | HSD17B10 (0.61) | ALDH1A1NPC1LMNAMAPTCASP3 | |
| SCHEMBL2554172 | 0.80 | MAOA (0.50) | ALDH1A1NPC1MAOAMAOBRAB9A | |
| SCHEMBL1959473 | 0.80 | CYSLTR2 (0.57) | ALDH1A1NPC1MAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |