Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808349 | 1.00 | CYP11B1 (0.61) | CYP11B1CYP11B2SMN1; SMN2MEN1LMNA | |
| SCHEMBL2062446 | 0.83 | MAPK14 (0.51) | SMN1; SMN2MEN1LMNAPOLBMAPT | |
| SCHEMBL29951958 | 0.83 | MAPK14 (0.51) | SMN1; SMN2MEN1LMNAPOLBMAPT | |
| 2-Phenyl-1H-Indole-3-Carbaldehyde SCHEMBL1429713 | 0.82 | ESR1 (0.55) | SMN1; SMN2MEN1MAPTKMT2ACYP19A1 | |
| SCHEMBL6488869 | 0.82 | SMN1; SMN2 (0.51) | CYP11B1CYP11B2SMN1; SMN2MEN1LMNA | |
| SCHEMBL1120931 | 0.81 | KDM4E (0.62) | CYP11B1CYP11B2SMN1; SMN2MAPTTUBB4A | |
| SCHEMBL15331532 | 0.81 | CHUK (0.49) | CYP11B1CYP11B2CHUKPIM1 | |
| SCHEMBL11095977 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2SMN1; SMN2MEN1LMNA | |
| SCHEMBL14519076 | 0.78 | GSK3B (0.53) | SMN1; SMN2MEN1LMNAMAPTKMT2A | |
| SCHEMBL2792363 | 0.76 | CYP11B2 (1.00) | CYP11B1CYP11B2SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |