Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336038 | 1.00 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ALDH3A1CHRNB2CHRNA4 | |
| SCHEMBL335598 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3KDM4EMEN1KMT2A | |
| SCHEMBL116316 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ALDH1A3ALDH3A1L3MBTL1MAPT | |
| SCHEMBL29436325 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ALDH1A3ALDH3A1L3MBTL1MAPT | |
| SCHEMBL30590409 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3KDM4EMEN1KMT2A | |
| SCHEMBL335600 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALDH1A3ALDH3A1KDM4EMEN1 | |
| SCHEMBL335730 | 0.75 | ALDH1A3 (0.41) | ALDH1A1ALDH1A3ALDH3A1KDM4EMEN1 | |
| SCHEMBL335566 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ALDH3A1MEN1KMT2A | |
| SCHEMBL31672969 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL335669 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482831-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | Satya Therapeutics, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |