Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557958 | 0.86 | ALDH1A3 (0.47) | ALDH1A3ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL29952637 | 0.84 | OGG1 (0.45) | ALDH1A1TDP1POLBHPGD | |
| SCHEMBL2558483 | 0.83 | ALDH1A3 (0.58) | ALDH1A3ALDH1A1LMNATDP1DRD1 | |
| SCHEMBL2557252 | 0.81 | ALDH1A3 (0.56) | ALDH1A3ALDH1A1LMNATDP1DRD1 | |
| SCHEMBL22100068 | 0.81 | HPGD (0.56) | TDP1POLBHPGD | |
| SCHEMBL29955555 | 0.79 | ALDH1A3 (0.53) | ALDH1A3ALDH1A1DRD1CYP2A6POLB | |
| SCHEMBL2561236 | 0.79 | ALDH1A3 (0.57) | ALDH1A3ALDH1A1LMNADRD1CYP2A6 | |
| SCHEMBL29957609 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL22099895 | 0.78 | GAA (0.50) | ALDH1A1LMNATDP1POLB | |
| SCHEMBL15332361 | 0.78 | ALDH1A3 (0.51) | ALDH1A3ALDH1A1LMNATDP1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |