Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 2/20 | 0.31 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247030 | 0.79 | HPGD (0.42) | PARP10POLBALDH1A1GRIN2DGRIN3B | |
| SCHEMBL29952760 | 0.78 | PARP10 (0.51) | PARP10EPHX2MAP4K4 | |
| SCHEMBL16397642 | 0.76 | POLB (0.38) | PARP10POLBKDM4EALDH1A1HDAC4 | |
| SCHEMBL29952314 | 0.76 | UNG (0.42) | PARP10FAAHEPHX2ALDH1A1 | |
| SCHEMBL14227724 | 0.76 | TLR4 (0.42) | PARP10 | |
| SCHEMBL18003236 | 0.75 | POLB (0.40) | PARP10POLBALDH1A1HDAC4MEF2D | |
| SCHEMBL18409872 | 0.75 | GRIN2D (0.36) | PARP10ALDH1A1MAP4K4GRIN2DGRIN3B | |
| SCHEMBL10169109 | 0.75 | CYP19A1 (0.48) | POLBALDH1A1 | |
| SCHEMBL2692882 | 0.74 | SRC (0.50) | POLBALDH1A1HDAC4EP300MEF2D | |
| SCHEMBL29956659 | 0.74 | SRC (0.50) | POLBALDH1A1HDAC4EP300MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |