SCHEMBL16397642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18003236	0.98	POLB (0.40)	POLBPARP10ALDH1A1SLC6A2SLC6A4
	SCHEMBL16247030	0.85	HPGD (0.42)	POLBPARP10ALDH1A1HPGDMAOB
	SCHEMBL16399167	0.85	SLC6A2 (0.41)	POLBPARP10ALDH1A1SLC6A2SLC6A4
	SCHEMBL18003168	0.84	SLC6A2 (0.32)	ALDH1A1SLC6A2SLC6A4SLC6A3
	SCHEMBL6122852	0.81	BRD4 (0.39)	FFAR4KMT2A
	SCHEMBL18003876	0.81	SLC6A2 (0.41)	POLBPARP10ALDH1A1SLC6A2SLC6A4
	SCHEMBL16406695	0.79	FFAR1 (0.37)	POLBPARP10ALDH1A1HPGDMAOB
	SCHEMBL5610574	0.79	CYP1A1 (0.42)	POLBALDH1A1KMT2AABL1PPARG
	SCHEMBL13078055	0.78	FFAR4 (0.42)	POLBPARP10SLC6A2SLC6A4SLC6A3
	SCHEMBL10174918	0.78	PARP10 (0.40)	POLBPARP10SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.