Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454234 | 0.87 | MGLL (0.43) | MGLLHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL1181323 | 0.80 | CA2 (0.36) | MGLLALDH1A1KDM4ETSHR | |
| SCHEMBL29955062 | 0.80 | MGLL (0.38) | MGLLHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL21932635 | 0.78 | HSP90AA1 (0.48) | MGLLHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL29958230 | 0.78 | HSP90AA1 (0.40) | MGLLHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL29193016 | 0.78 | MGLL (0.36) | MGLLHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL2557427 | 0.77 | MGLL (0.33) | MGLLKDM4E | |
| SCHEMBL29955530 | 0.74 | GAA (0.42) | MGLLHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL2724555 | 0.74 | GAA (0.42) | MGLLHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL25406786 | 0.73 | TLR8 (0.41) | MGLLALDH1A1KDM4EGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |