Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441518 | 1.00 | ERN1 (0.37) | ERN1BTKNFE2L2CCR1CCR5 | |
| SCHEMBL772591 | 0.83 | ERN1 (0.46) | ERN1BTKNFE2L2MEN1KMT2A | |
| SCHEMBL29162822 | 0.81 | SMN1; SMN2 (0.43) | MEN1KMT2ALRRK2NOS3NOS2 | |
| SCHEMBL746493 | 0.81 | ERN1 (0.44) | ERN1ALDH1A1 | |
| SCHEMBL25230147 | 0.79 | ERN1 (0.36) | ERN1BTKNFE2L2MEN1KMT2A | |
| SCHEMBL438652 | 0.79 | NFE2L2 (0.42) | ERN1BTKNFE2L2MEN1KMT2A | |
| SCHEMBL31563047 | 0.79 | ERN1 (0.36) | ERN1BTKNFE2L2CCR1CCR5 | |
| SCHEMBL16333419 | 0.79 | AURKA (0.40) | ERN1BTKNFE2L2MEN1KMT2A | |
| SCHEMBL613366 | 0.79 | ERN1 (0.36) | ERN1BTKNFE2L2CCR1CCR5 | |
| SCHEMBL29993110 | 0.79 | TRPV4 (0.43) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |