Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MOK | Q9UQ07 | 3/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790236 | 0.80 | MAPT (0.47) | ALDH1A1NPC1POLBMAPTRAB9A | |
| SCHEMBL4806828 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL6177644 | 0.78 | KDM4E (0.57) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL10777773 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL3000836 | 0.78 | NPC1 (0.47) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL24022846 | 0.78 | MOK (0.47) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL9224255 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL30881591 | 0.76 | HDAC1 (0.55) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL23795788 | 0.76 | HDAC1 (0.55) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL3000834 | 0.75 | NEU3 (0.48) | ALDH1A1HTTNPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |