Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806828 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL6177644 | 0.80 | KDM4E (0.57) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL3000836 | 0.80 | NPC1 (0.47) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL24022846 | 0.80 | MOK (0.47) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL10777773 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL3000834 | 0.78 | NEU3 (0.48) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL29954819 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL10479168 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL11280566 | 0.78 | L3MBTL1 (0.43) | ALDH1A1HTTNPC1POLBMAPT | |
| SCHEMBL10852754 | 0.77 | CA1 (0.60) | ALDH1A1NPC1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384423-A | Intermediates for antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1995-01-24 | — | — | US | disclosed |
| US-5240960-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1993-08-31 | — | — | US | disclosed |