SCHEMBL29954828

SCHEMBL29954828

Nc1cncc(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
LMNA P02545 1/20 1.00
DDO Q99489 1/20 1.00
HCAR2 Q8TDS4 7/20 0.57
POLB P06746 1/20 0.57
MKNK1 Q9BUB5 1/20 0.50
MKNK2 Q9HBH9 1/20 0.50
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
APP P05067 1/20 0.43
GAA P10253 1/20 0.43
HCAR3 P49019 1/20 0.43
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185913 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL9448329 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL6743012 0.84 KDM4E (0.71) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL27750302 0.84 KDM4E (0.72) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL51830 0.83 HCAR2 (0.70) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL520949 0.82 KDM4E (0.69) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL30033490 0.82 KDM4E (0.69) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL4035571 0.82 CYP2C9 (0.79) ALDH1A1KDM4EMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL7124062 0.80 HCAR2 (0.67) ALDH1A1KDM4EMEN1KMT2ALMNA
Fluoride SCHEMBL21331909 0.80 HCAR2 (0.67) ALDH1A1KDM4EMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115245816-B Amino-nicotinic acid mixed mode chromatographic stationary phase and preparation method and application thereof 河北工业大学 2024-01-23 CN claimed
CN-115245816-A Amino nicotinic acid mixed-mode chromatographic stationary phase and preparation method and application thereof 河北工业大学 2022-10-28 CN claimed
CN-121372496-A Carbon nitride containing electron trap, preparation method thereof and application of carbon nitride in photocatalytic hydrogen peroxide generation 湖北大学 2026-01-23 CN disclosed
CN-119455003-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-119454801-A Nauclea extract capsule and its production process 海南森祺制药有限公司 2025-02-18 CN disclosed
CN-119455004-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-113660957-B Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2024-12-13 CN disclosed
CN-118637666-A Loose lithium-extracting electrode material and preparation method and application thereof 广东邦普循环科技有限公司 2024-09-13 CN disclosed
CN-115245816-B Amino-nicotinic acid mixed mode chromatographic stationary phase and preparation method and application thereof 河北工业大学 2024-01-23 CN disclosed
CN-116732783-A Metal organic framework composite antibacterial film and preparation method thereof 福建农林大学 2023-09-12 CN disclosed
CN-115245816-A Amino nicotinic acid mixed-mode chromatographic stationary phase and preparation method and application thereof 河北工业大学 2022-10-28 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed