Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285130 | 1.00 | LMNA (0.47) | LMNARAB9ANPSR1KDM4EMAPK1 | |
| SCHEMBL9288161 | 0.86 | ALDH1A1 (0.40) | LMNARAB9ANPSR1KDM4EMAPK1 | |
| SCHEMBL192661 | 0.84 | LMNA (0.55) | LMNARAB9ANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL8532660 | 0.81 | KDM4E (0.39) | LMNARAB9ANPSR1KDM4EMAPK1 | |
| SCHEMBL31627684 | 0.80 | KDM4E (0.37) | LMNARAB9ANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL5674047 | 0.80 | KDM4E (0.37) | LMNARAB9ANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL9287288 | 0.79 | LMNA (0.38) | LMNARAB9ANPSR1KDM4EMAPK1 | |
| SCHEMBL6364307 | 0.77 | LMNA (0.50) | LMNARAB9ANPSR1KDM4EMAPK1 | |
| SCHEMBL12640264 | 0.77 | KDM4E (0.35) | LMNANPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL10951849 | 0.75 | LMNA (0.34) | LMNANPSR1KDM4EMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |