Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547551 | 0.92 | KDM4E (0.50) | CYP1A2LMNACYP2D6SCN1ASCN2A | |
| SCHEMBL3537247 | 0.90 | KDM4E (0.53) | CYP1A2LMNACYP2D6SCN1ASCN2A | |
| SCHEMBL3992307 | 0.79 | LMNA (0.39) | CYP1A2LMNACYP2D6SCN1ASCN2A | |
| SCHEMBL21945580 | 0.79 | METAP1 (0.41) | CYP1A2LMNACYP2D6SCN1ASCN2A | |
| SCHEMBL27999409 | 0.76 | CYP3A4 (0.37) | CYP1A2LMNACYP2D6SCN1ASCN2A | |
| SCHEMBL10568062 | 0.76 | HTT (0.43) | LMNAL3MBTL1KDM4E | |
| SCHEMBL2548071 | 0.75 | CYP2D6 (0.39) | CYP1A2LMNACYP2D6SCN1ASCN2A | |
| SCHEMBL14844482 | 0.74 | METAP1 (0.43) | CYP1A2KDM4EMETAP1ANPEPERAP2 | |
| SCHEMBL14844484 | 0.74 | METAP1 (0.43) | CYP1A2KDM4EMETAP1ANPEPERAP2 | |
| SCHEMBL4919308 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |