Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 4/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844482 | 1.00 | METAP1 (0.43) | METAP1ANPEPERAP2PTGS1SLC7A11 | |
| SCHEMBL28380251 | 0.90 | ANPEP (0.56) | ANPEPERAP2KDM4EGRIK1GRIK2 | |
| SCHEMBL28380252 | 0.90 | ANPEP (0.56) | ANPEPERAP2KDM4EGRIK1GRIK2 | |
| SCHEMBL2235415 | 0.79 | METAP1 (0.45) | METAP1GRIK1GRIK2GRM8GRM6 | |
| SCHEMBL2235419 | 0.79 | METAP1 (0.45) | METAP1GRIK1GRIK2GRM8GRM6 | |
| SCHEMBL28363515 | 0.77 | GFPT1 (0.33) | METAP1GFPT1 | |
| SCHEMBL1768254 | 0.76 | EPHX1 (0.50) | KDM4EGFPT1BLM | |
| SCHEMBL1768252 | 0.76 | EPHX1 (0.50) | KDM4EGFPT1BLM | |
| SCHEMBL2235588 | 0.76 | METAP1 (0.50) | METAP1GRIK1GRIK2GRM8GRM6 | |
| SCHEMBL2235591 | 0.76 | METAP1 (0.50) | METAP1GRIK1GRIK2GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| CN-115093463-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3201218-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| CN-105324390-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| CN-105849119-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-01-19 | — | — | CN | disclosed |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2020-11-10 | — | — | US | disclosed |
| CN-111770932-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2020-10-13 | — | — | CN | disclosed |
| EP-3707153-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2020-09-16 | — | — | EP | disclosed |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-03-03 | — | — | US | disclosed |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-02-25 | — | — | US | disclosed |
| CN-105324390-A | Beta-hairpin peptidomimetics | POLYPHOR AG | 2016-02-10 | — | — | CN | disclosed |
| EP-2978771-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978772-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2014-09-25 | — | — | US | disclosed |
| EP-2764010-A1 | TEMPLATE -FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | Polyphor Ag (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050346-A1 | TEMPLATE -FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | FPR1, FPR3, FPR2 | METAP1 232/4885ANPEP 467/4885ERAP2 702/4885 |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, C1S, BACE1 | METAP1 152/4885ANPEP 357/4885ERAP2 476/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | METAP1 709/4885ANPEP 139/4885ERAP2 1648/4885 |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | C1S, POLL, BACE1 | METAP1 200/4885ANPEP 294/4885ERAP2 464/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | METAP1 695/4885ANPEP 103/4885ERAP2 1118/4885 |
| US-10829520-B2 | Beta-hairpin peptidomimetics | POLQ, POLL, POLM | METAP1 594/4885ANPEP 178/4885ERAP2 1858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.