Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956019 | 0.88 | POLB (0.42) | POLBCSNK2A1LNPEPLOXLOXL2 | |
| SCHEMBL29954499 | 0.80 | POLB (0.42) | POLBKDM4EALDH1A1LMNA | |
| SCHEMBL29957189 | 0.78 | PDE4A (0.45) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29953202 | 0.73 | KMO (0.44) | POLBKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL29955297 | 0.73 | POLB (0.42) | POLB | |
| SCHEMBL29954303 | 0.73 | POLB (0.36) | POLBCSNK2A1LOXLOXL2 | |
| SCHEMBL29955920 | 0.73 | CSNK2A1 (0.54) | POLBCSNK2A1LOXLOXL2PDE4A | |
| SCHEMBL29952137 | 0.72 | AOC3 (0.40) | POLBCSNK2A1LOX | |
| SCHEMBL29957202 | 0.72 | POLB (0.37) | POLBCSNK2A1ALDH1A1LOXLOXL2 | |
| SCHEMBL29951840 | 0.71 | POLB (0.42) | POLBKDM4EALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |