Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954499 | 0.87 | POLB (0.42) | POLBTRPC6FEN1MCHR1ALOX5AP | |
| SCHEMBL29956019 | 0.80 | POLB (0.42) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29955972 | 0.80 | PDE4A (0.46) | POLBTRPC6MKNK1MKNK2PDE4A | |
| SCHEMBL29955501 | 0.78 | POLB (0.43) | POLB | |
| SCHEMBL29957502 | 0.78 | KMO (0.45) | POLBKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL29956041 | 0.75 | POLB (0.40) | POLBKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL21045685 | 0.75 | IKBKB (0.38) | POLBTRPC6FEN1MCHR1ALOX5AP | |
| SCHEMBL29952250 | 0.73 | POLB (0.40) | POLBMCHR1KDM4EALDH1A1RORC | |
| SCHEMBL29950803 | 0.72 | POLB (0.37) | POLBTRPC6FEN1MCHR1MKNK1 | |
| SCHEMBL22834682 | 0.72 | TRPC6 (0.40) | POLBTRPC6FEN1MCHR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |