Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238550 | 0.87 | ATM (0.56) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL29957193 | 0.85 | KMT2A (0.51) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL3759687 | 0.85 | KMT2A (0.51) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL20632883 | 0.81 | TSHR (0.50) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL7235160 | 0.80 | NPC1 (0.56) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL17064571 | 0.80 | ATM (0.47) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL17064867 | 0.80 | ATM (0.47) | ATMKMT2AHTTMEN1HPGD | |
| SCHEMBL1462874 | 0.80 | HTT (0.51) | KMT2AHTTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29957392 | 0.79 | ALDH1A1 (0.44) | ATMKMT2AHTTHPGDCYP3A4 | |
| SCHEMBL20632970 | 0.78 | ATM (0.45) | ATMKMT2AHTTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |