Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759687 | 1.00 | KMT2A (0.51) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL29954895 | 0.85 | ATM (0.45) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL4604584 | 0.85 | ATM (0.63) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL29957392 | 0.84 | ALDH1A1 (0.44) | KMT2AHTTHPGDATML3MBTL1 | |
| SCHEMBL14282753 | 0.82 | ALDH1A1 (0.53) | KMT2AHTTMEN1ATML3MBTL1 | |
| SCHEMBL3784889 | 0.81 | ALDH1A1 (0.41) | KMT2AHTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL29563535 | 0.80 | TP53 (0.51) | KMT2AMEN1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL559935 | 0.80 | TP53 (0.51) | KMT2AMEN1SMN1; SMN2CYP3A4TP53 | |
| SCHEMBL3319951 | 0.79 | CYP3A4 (0.70) | KMT2ASMN1; SMN2CYP3A4TP53ALDH1A1 | |
| SCHEMBL13307458 | 0.79 | ATM (0.56) | KMT2AHTTMEN1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |