Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556951 | 0.79 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2APSEN1PSEN2 | |
| SCHEMBL2556336 | 0.75 | NPC1 (0.36) | MEN1ALDH1A1KMT2ATDP1PSEN1 | |
| SCHEMBL2557305 | 0.73 | SRC (0.43) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2555346 | 0.72 | SRC (0.38) | TDP1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29346880 | 0.71 | DDB1 (0.35) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29956283 | 0.70 | ALDH1A1 (0.43) | ALDH1A1DDB1CRBNCCR2HPGD | |
| SCHEMBL31729987 | 0.69 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2ATDP1HPGD | |
| SCHEMBL29954114 | 0.69 | PDE4B (0.51) | ALDH1A1TDP1HPGD | |
| SCHEMBL29954892 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1HPGDMAPT | |
| SCHEMBL2561769 | 0.68 | ALDH1A1 (0.40) | MEN1ALDH1A1KMT2APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |