Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953300 | 0.89 | ENPP2 (0.41) | ENPP2LIPERXRARXRBRXRG | |
| SCHEMBL29955034 | 0.78 | DYRK1A (0.40) | MAPTALDH1A1L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL3188971 | 0.77 | ENPP2 (0.57) | ENPP2MAPTALDH1A1HSD17B10ORAI1 | |
| SCHEMBL264406 | 0.77 | ENPP2 (0.57) | ENPP2LIPERXRARXRBRXRG | |
| SCHEMBL29417492 | 0.77 | ENPP2 (0.57) | ENPP2LIPERXRARXRBRXRG | |
| SCHEMBL29953225 | 0.77 | ENPP2 (0.57) | ENPP2MAPTALDH1A1HSD17B10ORAI1 | |
| SCHEMBL29875461 | 0.76 | MAPT (0.50) | ENPP2LIPEMAPTALDH1A1KDM4E | |
| SCHEMBL1427222 | 0.76 | MAPT (0.50) | ENPP2LIPEMAPTALDH1A1KDM4E | |
| SCHEMBL16852474 | 0.76 | CYP1A2 (0.52) | ALDH1A1L3MBTL1KCNK3KCNK9EPHX2 | |
| SCHEMBL29955431 | 0.75 | ENPP2 (0.37) | ENPP2LIPEMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |