Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318515 | 0.81 | PDE4A (0.49) | KDM4ECYP3A4ALOX12TDP1GAA | |
| SCHEMBL26375275 | 0.80 | PSMD14 (0.51) | DYRK1AKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL29954928 | 0.78 | ENPP2 (0.37) | KDM4EL3MBTL1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL19836985 | 0.77 | KMT2A (0.50) | DYRK1AKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL31179075 | 0.77 | HSP90AA1 (0.51) | DYRK1AKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL29862875 | 0.77 | KMT2A (0.50) | DYRK1AKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL24910162 | 0.77 | DYRK1A (0.40) | DYRK1AKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL28594857 | 0.74 | LIPE (0.55) | KDM4ETDP1L3MBTL1NPC1PKM | |
| SCHEMBL23714062 | 0.74 | MEN1 (0.45) | DYRK1AKDM4ECYP3A4ALOX12TDP1 | |
| SCHEMBL5128448 | 0.73 | SSTR4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |