Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343158 | 1.00 | KDM4E (0.52) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2341924 | 0.91 | ALDH1A1 (0.48) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2345150 | 0.90 | NPSR1 (0.49) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2348488 | 0.87 | MAPT (0.48) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2345076 | 0.87 | HTT (0.38) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2345291 | 0.87 | NPSR1 (0.44) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2347546 | 0.87 | LMNA (0.47) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2346039 | 0.87 | LMNA (0.50) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2346329 | 0.87 | CYP1A2 (0.51) | KDM4EATML3MBTL1ALDH1A1LMNA | |
| SCHEMBL2349756 | 0.85 | LMNA (0.50) | KDM4EATML3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |