Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.40 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.40 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953650 | 0.81 | LIPE (0.54) | LIPEENPP2RAB9APOLBNPC1 | |
| SCHEMBL2558777 | 0.80 | AKR1C3 (0.36) | LIPEENPP2AKR1C3MAPTMAPK1 | |
| SCHEMBL2558775 | 0.80 | AKR1C3 (0.36) | LIPEENPP2AKR1C3MAPTMAPK1 | |
| SCHEMBL28821754 | 0.80 | LIPE (0.56) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL11305271 | 0.79 | GAA (0.55) | JAK2LMNAGAAMAPTHPGD | |
| SCHEMBL29954244 | 0.79 | LIPE (0.54) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL2558403 | 0.78 | AKR1C3 (0.37) | LIPEAKR1C3RAB9APOLBGAA | |
| SCHEMBL2558400 | 0.78 | AKR1C3 (0.37) | LIPEAKR1C3RAB9APOLBGAA | |
| SCHEMBL1907827 | 0.76 | CA1 (0.52) | POLBLMNATSHRMAPK1HSD17B10 | |
| SCHEMBL27397678 | 0.76 | ALDH1A1 (0.46) | RAB9ALMNAMAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |