SCHEMBL29955066

SCHEMBL29955066

CCCc1nn(C)c(Br)c1C=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PDE5A O76074 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956755 0.85 GAA (0.36)
SCHEMBL3605937 0.79 RAB9A (0.37) SMN1; SMN2LMNANPC1RAB9APDE5A
SCHEMBL15330332 0.77 NMT1 (0.31)
SCHEMBL29954230 0.73 LMNA (0.41) LMNANPC1RAB9APDE5A
SCHEMBL12283539 0.72 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL15334067 0.72 ENPP1 (0.38) SMN1; SMN2LMNANPC1RAB9A
SCHEMBL29956155 0.71 SMN1; SMN2 (0.42) SMN1; SMN2LMNANPC1RAB9A
SCHEMBL29957828 0.69 LMNA (0.30) LMNANPC1RAB9A
SCHEMBL29955801 0.67
SCHEMBL29953870 0.67 GLP1R (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed