Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955098 | 0.83 | ENPP2 (0.44) | ENPP2CA2CA1TSHRCYP2C9 | |
| SCHEMBL5247264 | 0.83 | ENPP2 (0.44) | ENPP2CA2CA1TSHRGAA | |
| SCHEMBL23051 | 0.80 | ENPP2 (0.48) | ENPP2CA2CA1LPLLIPG | |
| SCHEMBL28686847 | 0.78 | ENPP2 (0.61) | ENPP2CA2CA1TSHRTDP1 | |
| SCHEMBL29408089 | 0.78 | ENPP2 (0.61) | ENPP2CA2CA1TSHRTDP1 | |
| SCHEMBL6890847 | 0.78 | ENPP2 (0.40) | PTPN1ENPP2CA2CA1LPL | |
| SCHEMBL5522353 | 0.78 | TSHR (0.44) | ENPP2CA2LPLLIPGTSHR | |
| SCHEMBL3590939 | 0.78 | XDH (0.51) | ENPP2 | |
| SCHEMBL6036396 | 0.77 | BACE1 (0.47) | PTPN1TSHRSMN1; SMN2GAATDP1 | |
| SCHEMBL10111073 | 0.76 | TSHR (0.51) | TSHRSMN1; SMN2GAATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |