Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563846 | 1.00 | LMNA (0.42) | LMNAMAPTL3MBTL1ATMNQO1 | |
| SCHEMBL1436749 | 0.87 | PDK2 (0.44) | MAPTL3MBTL1KMT2AKDM4EPDK2 | |
| SCHEMBL41862 | 0.81 | EPHX2 (0.44) | LMNAMAPTL3MBTL1ATMAR | |
| SCHEMBL29653552 | 0.81 | EPHX2 (0.44) | LMNAMAPTL3MBTL1ATMAR | |
| SCHEMBL15332562 | 0.80 | AR (0.50) | LMNAPDK2AR | |
| SCHEMBL5953481 | 0.80 | L3MBTL1 (0.43) | LMNAMAPTL3MBTL1ATMNQO1 | |
| SCHEMBL5953654 | 0.79 | MAPT (0.45) | LMNAMAPTL3MBTL1ATMNQO1 | |
| SCHEMBL10088500 | 0.78 | NQO1 (0.43) | LMNAMAPTL3MBTL1ATMNQO1 | |
| SCHEMBL29956388 | 0.78 | L3MBTL1 (0.44) | LMNAMAPTL3MBTL1ATMNQO1 | |
| SCHEMBL28050159 | 0.77 | NQO1 (0.46) | MAPTNQO1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |