Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 4/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462538 | 0.89 | TSHR (0.43) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL2553738 | 0.87 | CYP1A2 (0.33) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL22781596 | 0.87 | TSHR (0.42) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL28859749 | 0.87 | TSHR (0.42) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL25936321 | 0.85 | TSHR (0.40) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL3513093 | 0.84 | MAPT (0.36) | SMN1; SMN2 | |
| Formic Acid SCHEMBL1131732 | 0.83 | CA12 (0.40) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL1461505 | 0.82 | ADH1C (0.45) | TSHRTRPV1KDM5AADH1CADH1A | |
| SCHEMBL29957351 | 0.82 | TSHR (0.44) | CA12CA1CA9TSHRALDH1A1 | |
| SCHEMBL24113612 | 0.80 | ADH1C (0.48) | TSHRTRPV1KDM5AADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |