SCHEMBL3513093

SCHEMBL3513093

O=CCN(CCO)CCO

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2553738 0.88 CYP1A2 (0.33) MAPTKDM4EALOX15SMN1; SMN2
SCHEMBL18515796 0.88 ALDH1A1 (0.30) MAPTKDM4EALOX15SMN1; SMN2
SCHEMBL12464630 0.85
SCHEMBL29955232 0.84 CA12 (0.38) SMN1; SMN2
SCHEMBL22842446 0.84
SCHEMBL26296846 0.82 MEN1 (0.35)
SCHEMBL21861532 0.79 ALDH1A1 (0.41) ALOX15
SCHEMBL21698630 0.78
SCHEMBL6651598 0.78
SCHEMBL14535211 0.78 TDP1 (0.54) MAPTKDM4EALOX15SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-10035970-B2 Friction-reducing compound, method of producing same, and lubricant composition BASF SE (DE) 2018-07-31 US disclosed
US-10035970-B2 Friction-reducing compound, method of producing same, and lubricant composition BASF SE (DE) 2018-07-31 US disclosed
US-20170321147-A1 Friction-Reducing Compound, Method of Producing Same, and Lubricant Composition BASF SE (DE) 2017-11-09 US disclosed
US-20170321147-A1 Friction-Reducing Compound, Method of Producing Same, and Lubricant Composition BASF SE (DE) 2017-11-09 US disclosed
US-20160333003-A1 READ-THROUGH COMPOUND PRODRUGS SUPPRESSING PREMATURE NONSENSE MUTATIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-11-17 US disclosed
WO-2015109248-A1 READ-THROUGH COMPOUND PRODRUGS SUPPRESSING PREMATURE NONSENSE MUTATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-07-23 WO disclosed
US-8980242-B2 Aliphatic prodrug linker ASCENDIS PHARMA GMBH (DK) 2015-03-17 US disclosed
EP-1909845-B1 N,N-BIS-(2-HYDROXYETHYL) GLYCINE AMIDE AS LINKER IN POLYMER CONJUGATED PRODRUGS ASCENDIS PHARMA AS (DK) 2012-08-15 EP disclosed
US-20100291021-A1 ALIPHATIC PRODRUG LINKER ASCENDIS PHARMA GMBH (DE) 2010-11-18 US disclosed
EP-1909845-A2 N,N-BIS-(2-HYDROXYETHYL) GLYCINE AMIDE AS LINKER IN POLYMER CONJUGATED PRODRUGS Complex Biosystems GmbH (DE) 2008-04-16 EP disclosed
WO-2006136586-A2 N, N-BIS- (2-HYDROXYETHYL) GLYCINE AMIDE AS LINKER IN POLYMER CONJUGATED PRODRUGS COMPLEX BIOSYSTEMS GMBH (DE) 2006-12-28 WO disclosed
EP-0253275-B1 QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE Henkel Kommanditgesellschaft auf Aktien (DE) 1991-03-06 EP disclosed
EP-0253275-A1 Quaternary ammonium compounds and their use Henkel Kommanditgesellschaft auf Aktien (DE) 1988-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291021-A1 ALIPHATIC PRODRUG LINKER PAICS, AADAC, TK1 MAPT 986/4885KDM4E 2936/4885ALOX15 2151/4885
US-20160333003-A1 READ-THROUGH COMPOUND PRODRUGS SUPPRESSING PREMATURE NONSENSE MUTATIONS UPF1, NUDT21, RNMT MAPT 269/4885KDM4E 2100/4885ALOX15 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.