Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.34 |
| ▸ | MTOR | P42345 | 7/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439088 | 0.85 | ALOX5AP (0.39) | ALOX5APFEN1PIK3CDCA2CHKA | |
| SCHEMBL2553149 | 0.78 | ALOX5AP (0.45) | ALOX5APFEN1PIK3CDERN1PIK3CA | |
| SCHEMBL16558767 | 0.78 | ERN1 (0.36) | PIK3CDERN1ASPHPIK3CAPIK3R1 | |
| SCHEMBL16712832 | 0.76 | CA2 (0.45) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL29952510 | 0.75 | ALOX5AP (0.39) | ALOX5APFEN1ERN1NOS3NOS2 | |
| Formic Acid SCHEMBL30949963 | 0.74 | NOS3 (0.46) | PIK3CDCA2CHKANOS3NOS2 | |
| SCHEMBL2562852 | 0.73 | FEN1 (0.56) | ALOX5APFEN1NOS3NOS2EGFR | |
| SCHEMBL2966961 | 0.73 | ERN1 (0.40) | ERN1 | |
| SCHEMBL20772336 | 0.72 | PIK3CD (0.42) | ALOX5APFEN1PIK3CDCA2CHKA | |
| SCHEMBL24858337 | 0.71 | NOS3 (0.56) | PIK3CDCA2CHKANOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |