Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954227 | 0.81 | TSHR (0.49) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL21397712 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL140950 | 0.78 | TSHR (0.59) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL4869503 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL6130008 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL705421 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL10685820 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL983428 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL10746854 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBTDP1TSHR | |
| SCHEMBL1641498 | 0.74 | TSHR (0.56) | ALDH1A1MAPTPOLBTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |