Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126184 | 0.84 | SYK (0.38) | ALDH1A1L3MBTL1GAAKDRLMNA | |
| SCHEMBL5681020 | 0.81 | HTT (0.38) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL21598618 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL4005263 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL5677055 | 0.80 | KDR (0.38) | ALDH1A1L3MBTL1KMT2AMEN1KDR | |
| SCHEMBL5126193 | 0.76 | ADORA1 (0.47) | SMN1; SMN2ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL6094043 | 0.74 | TACR1 (0.42) | ALDH1A1L3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL1375331 | 0.74 | L3MBTL1 (0.45) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EKMT2A | |
| SCHEMBL16611723 | 0.73 | KDR (0.42) | ALDH1A1L3MBTL1MAPTKDRCYP1A2 | |
| SCHEMBL29728357 | 0.73 | KDR (0.42) | ALDH1A1L3MBTL1MAPTKDRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |