Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.70 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.70 |
| ▸ | KMO | O15229 | 2/20 | 0.67 |
| ▸ | UNG | P13051 | 1/20 | 0.65 |
| ▸ | ERN1 | O75460 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711947 | 1.00 | TRIM24 (0.70) | TRIM24TRIM33KMOUNGERN1 | |
| SCHEMBL12212910 | 1.00 | TRIM24 (0.70) | TRIM24TRIM33KMOUNGERN1 | |
| SCHEMBL29952036 | 0.87 | UNG (0.79) | TRIM24TRIM33KMOUNGERN1 | |
| SCHEMBL2587878 | 0.87 | UNG (0.79) | TRIM24TRIM33KMOUNGERN1 | |
| SCHEMBL29577419 | 0.87 | KMO (0.87) | TRIM24TRIM33KMOERN1GAA | |
| SCHEMBL14683877 | 0.87 | KMO (0.87) | TRIM24TRIM33KMOERN1GAA | |
| SCHEMBL3220396 | 0.85 | KMO (0.91) | TRIM24TRIM33KMOERN1GAA | |
| SCHEMBL437537 | 0.84 | KMO (0.91) | KMOERN1GAALMNARXRA | |
| SCHEMBL1676039 | 0.84 | KMO (0.65) | TRIM24TRIM33KMOUNGERN1 | |
| SCHEMBL1348028 | 0.84 | ERN1 (0.65) | TRIM24TRIM33KMOERN1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |