Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222046 | 0.82 | KDM4E (0.46) | KDM4EIDO1ROCK1ALDH1A1PTPN1 | |
| SCHEMBL10385134 | 0.81 | KDM4E (0.45) | KDM4EIDO1TDO2ROCK1ALDH1A1 | |
| SCHEMBL29952506 | 0.79 | LMNA (0.42) | KDM4EIDO1TDO2ALDH1A1PTPN1 | |
| SCHEMBL29956049 | 0.79 | CYP2A6 (0.47) | KDM4EIDO1ALDH1A1PTPN1CYP2A6 | |
| SCHEMBL1254005 | 0.79 | ROCK1 (0.49) | KDM4EROCK1CYP2A6PIM1PIM2 | |
| SCHEMBL16934955 | 0.76 | KDM4E (0.41) | KDM4EROCK1CYP2A6PIM1PIM2 | |
| SCHEMBL13062396 | 0.74 | LIMK1 (0.50) | KDM4EIDO1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4730528 | 0.71 | BCKDK (0.53) | KDM4EALDH1A1HPGDPTPN1TDP1 | |
| SCHEMBL9404678 | 0.70 | KDM4E (0.41) | KDM4ESTK17BIDO1TDO2ROCK1 | |
| SCHEMBL3258493 | 0.70 | KDM4E (0.61) | KDM4ESTK17BIDO1TDO2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |