Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 5/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957282 | 0.89 | ALDH1A1 (0.37) | ALDH1A1TLR8TDP1L3MBTL1GAA | |
| SCHEMBL24915248 | 0.82 | ALDH1A1 (0.39) | ALDH1A1GAACCR1KMT2A | |
| SCHEMBL29950723 | 0.82 | ALDH1A1 (0.39) | ALDH1A1GAACCR1KMT2A | |
| SCHEMBL2557221 | 0.78 | FGFR4 (0.36) | ALDH1A1CCR1TSHRKMT2A | |
| SCHEMBL29950759 | 0.74 | SORD (0.46) | ALDH1A1CCR1KMT2A | |
| SCHEMBL28281051 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CCR1KMT2A | |
| SCHEMBL1767822 | 0.74 | TLR8 (0.38) | TLR8PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29956022 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CCR1KMT2A | |
| SCHEMBL29956619 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAACCR1KDM5AKDM5B | |
| SCHEMBL29954755 | 0.74 | CCR1 (0.39) | ALDH1A1L3MBTL1GAACCR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |