Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555444 | 0.89 | SRC (0.52) | SRCRAB9AKDM4ENFE2L2NPC1 | |
| SCHEMBL29958222 | 0.84 | PTGDR2 (0.56) | RAB9AKDM4ENPC1MAPK1GBA1 | |
| SCHEMBL29952197 | 0.83 | ALDH1A1 (0.56) | SRCRAB9AKDM4ENFE2L2NPC1 | |
| SCHEMBL20150988 | 0.82 | SRC (0.56) | SRCRAB9AKDM4ENFE2L2NPC1 | |
| SCHEMBL2555240 | 0.82 | SRC (0.56) | SRCRAB9AKDM4ENFE2L2NPC1 | |
| SCHEMBL2554954 | 0.82 | SRC (0.50) | SRCRAB9ANFE2L2NPC1TLR2 | |
| SCHEMBL2561415 | 0.81 | SMN1; SMN2 (0.47) | SRCRAB9AKDM4ENPC1MAPK1 | |
| SCHEMBL2556798 | 0.81 | HSD17B10 (0.53) | SRCRAB9AKDM4ENFE2L2NPC1 | |
| SCHEMBL2557724 | 0.80 | SRC (0.50) | SRCRAB9AKDM4ENFE2L2NPC1 | |
| SCHEMBL15330537 | 0.79 | SRC (0.55) | SRCRAB9AKDM4ENFE2L2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |