SCHEMBL29956023

SCHEMBL29956023

Cc1ccc(-c2[nH]c3c(F)cc(F)cc3c2C=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APOL1 O14791 17/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2560395 0.90 APOL1 (0.40) APOL1
SCHEMBL29952794 0.90 APOL1 (0.52) APOL1
SCHEMBL15331317 0.86 MAP2 (0.39) APOL1
SCHEMBL15330244 0.86 SMN1; SMN2 (0.39) APOL1
SCHEMBL15331379 0.86 APOL1 (0.44) APOL1
SCHEMBL15332815 0.86 APOL1 (0.46) APOL1
SCHEMBL2553956 0.85 APOL1 (0.41) APOL1
SCHEMBL29950808 0.85 APOL1 (0.37) APOL1
SCHEMBL29952478 0.85 APOL1 (0.44) APOL1
SCHEMBL2557992 0.85 APOL1 (0.40) APOL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed