Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 11/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559575 | 0.91 | PTGES (0.37) | APOL1PTGESALOX5KDM4EALDH1A1 | |
| SCHEMBL29958310 | 0.88 | CNR1 (0.41) | APOL1GSK3AGSK3BALDH1A1LMNA | |
| SCHEMBL15331128 | 0.88 | L3MBTL1 (0.38) | PTGESALOX5FEN1KDM4EALDH1A1 | |
| SCHEMBL2555973 | 0.88 | MAP2 (0.42) | APOL1PTGESALOX5FEN1KDM4E | |
| SCHEMBL15333244 | 0.87 | TP53 (0.41) | PTGESALOX5CSNK1DCSNK1EMAPK14 | |
| SCHEMBL29956023 | 0.85 | APOL1 (0.44) | APOL1 | |
| SCHEMBL2558435 | 0.85 | APOL1 (0.37) | APOL1GSK3AGSK3BPTGESALOX5 | |
| SCHEMBL15331261 | 0.85 | ALDH1A1 (0.41) | APOL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL24884872 | 0.82 | ACHE (0.38) | APOL1GSK3AGSK3BPTGESALOX5 | |
| SCHEMBL2551809 | 0.82 | PTGES (0.36) | PTGESALOX5FEN1CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |