Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31573430 | 1.00 | ERN1 (0.42) | ERN1ALDH1A1SRCTDP1KDM4E | |
| SCHEMBL29957844 | 0.85 | ERN1 (0.42) | ERN1ALDH1A1SRCTDP1KDM4E | |
| SCHEMBL4983077 | 0.79 | ALDH1A1 (0.53) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL29953846 | 0.79 | NNMT (0.50) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL30211775 | 0.79 | ALDH1A1 (0.53) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL587068 | 0.79 | NNMT (0.50) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL25224579 | 0.78 | PRKDC (0.52) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL10321799 | 0.78 | ALDH1A1 (0.42) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL17161149 | 0.78 | ERN1 (0.51) | ERN1ALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL587088 | 0.78 | ERN1 (0.42) | ERN1ALDH1A1SRCTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |