Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600125 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL29956017 | 0.87 | ALDH1A1 (0.54) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL1460104 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL29954218 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL30989179 | 0.77 | ALDH1A1 (0.62) | LMNAALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL14419604 | 0.77 | POLB (0.56) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL12077562 | 0.76 | HTT (0.63) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL2634586 | 0.75 | ENPP2 (0.53) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2317288 | 0.75 | ALDH1A1 (0.65) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL16195782 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2LMNAHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |