Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952877 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EPOLBFDPS | |
| SCHEMBL8168327 | 0.82 | ESR1 (0.49) | ALDH1A1MIFKIF11 | |
| SCHEMBL29955996 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2POLBFDPS | |
| SCHEMBL29950918 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2POLBFDPS | |
| SCHEMBL27729422 | 0.81 | SIRT2 (0.44) | ALDH1A1KDM4EKIF11 | |
| SCHEMBL20397637 | 0.81 | KIF11 (0.46) | ALDH1A1KIF11 | |
| SCHEMBL4214065 | 0.81 | SIRT2 (0.44) | ALDH1A1KDM4EKIF11 | |
| SCHEMBL17203107 | 0.81 | ADORA2A (0.40) | ALDH1A1KIF11 | |
| Hydrochloric Acid SCHEMBL4219539 | 0.80 | SIRT2 (0.43) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19361279 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |