Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.40 |
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556200 | 0.91 | RARB (0.42) | LIPGLPLPLA2G4BRARBALDH1A1 | |
| SCHEMBL29953260 | 0.82 | SMPD1 (0.43) | TRPV1THRATHRB | |
| SCHEMBL13564083 | 0.80 | LIPG (0.57) | LIPGLPLTRPV1MGLLRARB | |
| SCHEMBL29954064 | 0.77 | LPL (0.62) | LIPGLPLTRPV1MGLLPLA2G4B | |
| SCHEMBL29957976 | 0.76 | TSHR (0.48) | ALDH1A1 | |
| SCHEMBL29955524 | 0.75 | LPL (0.66) | LIPGLPLTRPV1MGLLPLA2G4B | |
| SCHEMBL29953292 | 0.74 | LIPG (0.40) | LIPGLPLNR5A1PLA2G2DTHRB | |
| SCHEMBL29951761 | 0.73 | LIPG (0.42) | LIPGLPLTRPV1MGLLNR5A1 | |
| SCHEMBL1840226 | 0.73 | NR5A1 (0.61) | PLA2G4BNR5A1ESR1ADRA2AADORA3 | |
| SCHEMBL1837816 | 0.73 | NR5A1 (0.61) | PLA2G4BNR5A1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |