SCHEMBL29956084

SCHEMBL29956084

COc1ccc(C(C)=O)cc1CSCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
HPGD P15428 2/20 0.76
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
HSP90AA1 P07900 1/20 0.60
DNMT1 P26358 1/20 0.60
POLB P06746 3/20 0.58
MAPK1 P28482 1/20 0.57
PTGDR2 Q9Y5Y4 2/20 0.53
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
USP2 O75604 1/20 0.51
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29958248 0.86 HPGD (1.00) ALDH1A1HPGDMEN1KMT2AMAPK1
SCHEMBL29956593 0.86 ALDH1A1 (0.76) ALDH1A1HPGDMEN1KMT2AHSP90AA1
SCHEMBL7093110 0.80 ALDH1A1 (0.67) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL29952081 0.79 ALDH1A1 (0.65) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL6342125 0.78 ALDH1A1 (0.71) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL2333106 0.77 ALDH1A1 (0.62) ALDH1A1HPGDMEN1KMT2AHSP90AA1
SCHEMBL2335504 0.77 ALDH1A1 (0.62) ALDH1A1HPGDMEN1KMT2AHSP90AA1
SCHEMBL14003532 0.77 ALDH1A1 (0.69) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL13461886 0.75 ALDH1A1 (0.67) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL8649778 0.75 ALDH1A1 (0.67) ALDH1A1HPGDMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed