Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956084 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1HPGDPTGDR2 | |
| SCHEMBL3902396 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14667296 | 0.78 | CREBBP (0.64) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL5119766 | 0.77 | CREBBP (0.62) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL27967180 | 0.76 | CREBBP (0.57) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL29958267 | 0.76 | CREBBP (0.54) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL29952856 | 0.76 | CREBBP (0.54) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL29463757 | 0.74 | CREBBP (0.72) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3034164 | 0.74 | CREBBP (0.72) | ALDH1A1HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL29952391 | 0.74 | CREBBP (0.51) | ALDH1A1HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |