Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | RAF1 | P04049 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952314 | 0.82 | UNG (0.42) | EPHX2FAAHPARP10KMT2A | |
| SCHEMBL29952760 | 0.81 | PARP10 (0.51) | EPHX2PARP10 | |
| SCHEMBL3930464 | 0.80 | PLK1 (0.51) | HPGDSMN1; SMN2PLK1MEN1KMT2A | |
| SCHEMBL16348552 | 0.78 | HDAC8 (0.47) | RAF1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL29955607 | 0.75 | CA12 (0.42) | RAF1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL29956368 | 0.72 | GRM5 (0.46) | EPHX2RAF1GRM5 | |
| SCHEMBL3934286 | 0.72 | MMP13 (0.40) | RAF1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL29954729 | 0.72 | PTPN1 (0.36) | EPHX2FAAHPARP10 | |
| SCHEMBL29956100 | 0.71 | KAT2B (0.50) | HPGDTSHRSMN1; SMN2PLK1KAT2B | |
| SCHEMBL29957292 | 0.70 | KAT2B (0.52) | HPGDTSHRSMN1; SMN2KAT2BBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |