Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21084775 | 0.86 | PAX8 (0.46) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL12117478 | 0.80 | LIPE (0.43) | PAX8BRD4ALDH1A1TP53MAPT | |
| SCHEMBL24190075 | 0.79 | PAX8 (0.40) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL30346189 | 0.79 | PAX8 (0.40) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL29837226 | 0.79 | PAX8 (0.41) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL30568129 | 0.79 | PAX8 (0.41) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL6317211 | 0.79 | MEN1 (0.41) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL13311040 | 0.79 | PAX8 (0.41) | PAX8BRD4MEN1RAB9AKMT2A | |
| SCHEMBL27808345 | 0.77 | LIPE (0.46) | PAX8BRD4MEN1KMT2ATSPO | |
| SCHEMBL13299608 | 0.77 | TSHR (0.45) | ENPP2MEN1KMT2ATSPOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |