Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12536276 | 0.77 | MAPK13 (0.42) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL28159924 | 0.76 | ALDH1A1 (0.51) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL27965003 | 0.76 | MAPT (0.42) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL21863290 | 0.75 | MAPT (0.55) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL31583268 | 0.74 | MAPK13 (0.40) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL13106161 | 0.74 | NR3C1 (0.41) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL16506029 | 0.74 | MAPK13 (0.40) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL26590131 | 0.74 | MAPK13 (0.41) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL26581194 | 0.72 | TP53 (0.41) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 | |
| SCHEMBL16417281 | 0.71 | MAPK13 (0.38) | MAPK13EIF2AK2MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |