Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 11/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957350 | 0.76 | MAPK1 (0.62) | ALPL | |
| SCHEMBL7878964 | 0.73 | — | — | |
| SCHEMBL70577 | 0.73 | HCAR2 (0.59) | TP53ALPLCA12HCAR3HCAR2 | |
| SCHEMBL27865417 | 0.72 | ALPL (0.49) | TP53ALPLCA12RPA1HCAR3 | |
| SCHEMBL17065997 | 0.72 | ALPL (0.54) | TP53ALPL | |
| Hydrochloric Acid SCHEMBL11595364 | 0.71 | HCAR2 (0.57) | TP53ALPLCA12HCAR3HCAR2 | |
| SCHEMBL15648169 | 0.71 | — | — | |
| SCHEMBL19987833 | 0.71 | HCAR2 (0.57) | TP53ALPLCA12HCAR3HCAR2 | |
| SCHEMBL13363456 | 0.71 | — | — | |
| SCHEMBL1269795 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |