Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065997 | 0.81 | ALPL (0.54) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL285996 | 0.77 | MAPK1 (0.67) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL171413 | 0.77 | MAPK1 (0.67) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL68056 | 0.77 | MAPK1 (1.00) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL4757203 | 0.76 | MAPK1 (0.61) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL2628053 | 0.76 | MAPK1 (0.61) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL29956218 | 0.76 | TP53 (0.48) | ALPL | |
| SCHEMBL20517628 | 0.76 | MAPK1 (0.65) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL21630583 | 0.76 | MAPK1 (0.65) | MAPK1GAAALPLMAPTRAB9A | |
| SCHEMBL286531 | 0.76 | MAPK1 (0.65) | MAPK1GAAALPLMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |